University of Missouri School of Medicine MU Health School of Medicine

Ulus X. Atasoy, M.D.

Ulus Atasoy, M.D.

Surgery and Molecular Microbiology & Immunology
Email: atasoyu@missouri.edu
Phone: (573) 882-6512

Fields of Interest

  • Immunology

Education

  • MA and MD, 1984, University of Minnesota

Postdoctoral Training

  • UCLA, NIH and Duke University Medical School

Research

In our lab we work on understanding the mechanisms of posttranscriptional gene regulation. Whereas transcriptional gene regulation is well understood, in contrast posttranscriptional gene expression remains a "black box". The problem is that there are about 35,000 genes in the human genome but far greater numbers of proteins inside cells. Most of this diversity in the proteome is generated at the posttranscriptional level. RNA binding proteins (RBPs) modulate the export, stability and translation of their mRNA targets.

There are only several dozen RBPs known, but it is currently hypothesized that there may be up to 3,000 in mammalian cells. The cis-elements to which RBPs bind have been found to exist in 8% of human genes. Many of these genes are in very exciting and critical areas, including immune responses, signal transduction, cell growth and differentiation, hematopoiesis, transcriptional and translation control, nutrient transport, apoptosis and metabolism. We have developed, novel, cutting edge approaches which enable us to en masse identify in vivo targets of different RBPs using microarray technologies. Currently, in our lab we are investigating:
  • allergen driven models of asthma,
  • breast cancer oncogenesis,
  • and searching for new RBPs.
We welcome bright, inquisitive students who desire to become involved in cutting edge research, affecting a variety of biological processes.

 

Selected publications:

 

 



 
pat techasintan
Pat Techasintana
Graduate Student
 
kiene_j1
Julianne Kiene
Undergraduate Student
mavrakis_n
Nora Mavrakis
Undergraduate Student
rowles_j
Joe L. Rowes, III
Undergraduate Student
 
wilson_a
Andrea Wilson
Undergraduate Student
york_a1
Abigail York
Undergraduate Student
 
 


 

Graduate Students:

Matt Gubin
Matt Gubin, Ph.D.
Ph.D., MMI-VPB Graduate Program, University of Missouri, 2012
Current position:  Postdoc,  Robert Schreiber’s Lab
Washington University, St. Louis, MO.
Garrett
Garrett Dahm, M.S.
M.S., MMI-VPB Graduate Program, University of Missouri, 2012
Currently applying to Physician assistant's school.

chen-j1
Jing Chen
MS, Pathobiology Area Program, University of Missouri, 2013
Current position:  Postdoctoral Researcher, Carole Cramer Lab
Arkansas State University, Jonesboro, AR

Post Baccalaureate Research Education Program (PREP) students:
ross-j
Jolill Ross
BS, Chemistry, Spelman College, 2010
Current Position:  Graduate Student, University of Missouri, Columbia, MO

Daryle Watson
(Picture not available)
BS, Biology, Loyola Marymount University, 2010
Current Position:  Senior Research Chemist, ABC Labs, Inc., Columbia, MO

Undergraduate Students:
marcus adair
Marcus Adair
BA, Biology, University of Missouri, 2008
Current Position: Medical Student, Mayo Clinic, Rochester, MN
His story in Mizzou Wire
connie strouse
Connie Strouse
BS, Biological Sciences, University of Missouri, 2009
Current Position:  Medical Student, Case Western Reserve University, Cleveland, OH
Michael Boyd
Michael Boyd
BS, Biological Sciences, University of Missouri, 2010
Current Position:  Medical Student, Kansas City University of Medicine and Biosciences, Kansas City, MO
Sandy Goyette
Sandy Goyette
BS, Biological Sciences, University of Missouri, 2010
Current Position:   Graduate Student, University of Missouri, Columbia, MO
Joanna
Joanna Kimball
BS, Biological Sciences, University of Missouri, 2011
Current Position:  Medical Student, University of Missouri, Columbia, MO
 


Brennan Berwald
(Picture not available)
BS, Biological Sciences, University of Missouri, 2012
Current Postition:  Optometry Student, Southern College of Optometry, Memphis, TN

 


Meron Ghidey
(Picture not available)
BS, Biological Sciences, University of Missouri, 2013
Current Position:  Graduate Student, Baylor University, Dallas, TX

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