University of Missouri School of Medicine MU Health School of Medicine
News Divider
            


World Ophthalmology Congress Brings MU Discoveries Into Focus


Nanomedicine research could help millions suffering from corneal conditions

Mohan
Rajiv Mohan, PhD
A University of Missouri research program that examines how nanotechnology could treat corneal diseases will be featured at the 2010 World Ophthalmology Congress from June 5 to June 9, 2010. Rajiv Mohan, PhD, associate professor of ophthalmology at the MU School of Medicine, will present how nanoparticles could be paired with therapeutic genes to deliver new treatments to corneal tissue. The promising new therapy could help millions who suffer from corneal scarring, wounds and other conditions.

Mohan was one of only five basic scientists invited to make a presentation at the nanotechnology session of the meeting, which will draw more than 6,000 attendees to Berlin.

"Because the meeting is primarily for physicians to discuss clinical care, basic science research that is presented must be able to translate from the bench to the bedside," Mohan said. "This selection is a direct reflection of MU's commitment to translational research in ophthalmology and to discoveries campuswide."

The cornea is the dome-shaped surface that functions as the eye's outermost layer. It is the first line of defense in shielding the eye from injury as well as infections. Corneal haze, scarring and abnormal blood vessel development are among the leading causes of vision impairment in the world and affect approximately 1.5 million Americans every year. Abnormal wound healing due to corneal injury or infection has been shown to play a critical role in causing these and other corneal disorders and diseases.

Mohan's laboratory is researching how hybrid gold nanoparticles and biodegradable polymeric nanoparticles can be used as a nonviral carrier to deliver gene therapy to the cornea. The nanoparticle-based gene therapy has shown minimal side effects in preclinical studies.

"The current nonviral vectors, or gene delivery vehicles, are incapable of delivering therapeutic levels of genes into the cells of the cornea," Mohan said. "Nanoparticles, because they are smaller, could provide a less invasive option for delivering the gene therapy effectively while reducing the risk of infection and side effects from treatment."

Mohan's corneal gene therapy research is funded by more than $2.8 million in grants from the National Eye Institute and Department of Veterans Affairs. The Association for Research in Vision and Ophthalmology recently identified findings from his laboratory as among the "the newest and most innovative" in the field of nanotechnology for drug and gene delivery.

The World Ophthalmology Congress brings together ophthalmologists to enhance education and improve access to the highest quality eye care. More information about its efforts to preserve and restore vision is available at http://www.icoph.org/advancing_leadership/ico_commitments_programs.html


News and Events

Greg Flaker, MD Safer Drug Combination Found For Patients With Atrial Fibrillation
Newer blood thinner a better option for some patients

Greg Worsowicz, MD Worsowicz Named President-Elect of Medical Society
Organization represents physical medicine and rehab physicians

AAAS MU School of Medicine Launches LCME Re-accreditation Process
Reception kicks off process of accessing medical education program

AAAS Four Scientists Named AAAS
Fellows for Medical Research

Achievements may advance diagnosis
and treatment for patients

Annual Dialysis Conference MU Hosts World’s Largest Dialysis Conference for 35th Year
Event has brought in nearly 65,000 attendees representing 60 countries

Cook and Stannard Researchers Develop Preservation Method for Donor Tissue
Technology a ‘game-changer’ for patients with joint damage

Zweig Family Medicine Residency Program Ranked Among Nation's Best
Data came from a national evaluation of residency programs

Fadel Researchers Find Link to Daily Physical Activity, Vascular Health
Even a few days of inactivity can decrease function in certain blood vessels

Kimberly Hoffman, PhD New Test Measures Doctors' Ability to Deliver Patient-Centered Care
Assessment tool helps learners become more engaged with patients

Drinking and Sleep MU Researchers Find Alcohol Interferes with Sleep
Study finds alcohol affects the body's sleep homeostasis and can cause insomnia

Research Day MU Announces Awards at Health Sciences Research Day
Event features projects from student and physician researchers

Binge Drinking MU Researchers Identify Epigenetic Changes Caused by Binge Drinking
Overconsumption of alcohol triggers inflammatory response in the liver




Media Relations
University of Missouri Health System
One Hospital Drive, DC028.00
Columbia, MO 65212
24/7 on-call pager: (573) 876-0708

Mary Jenkins
jenkinsmg@health.missouri.edu
(573) 882-7299

Jeff Hoelscher
hoelscherj@health.missouri.edu
(573) 884-1608

Derek Thompson
thompsonder@health.missouri.edu
(573) 882-3323


Web Communications
University of Missouri Health System
One Hospital Drive, MA204G, DC018.00
Columbia, MO 65212
(573) 884-0298

Rich Gleba
glebar@health.missouri.edu
(573) 884-0298

Laura Gerding, APR
gerdingla@health.missouri.edu
(573) 882-9193

Velvet Hasner
hasnerv@health.missouri.edu
(573) 884-1115

Mike Muin
muinm@health.missouri.edu
(573) 884-7541



Printer Friendly
Follow us on Twitter!   Facebook   YouTube Videos   Instagram   Pinterest  
Website created and maintained by the Office of Communications. Contact the MU School of Medicine.
Revised: April 27, 2013 - Copyright © 2014 - Curators of the University of Missouri. All rights reserved. DMCA and other copyright information. An equal opportunity/access/affirmative action/pro-disabled and veteran employer.