University of Missouri School of Medicine MU Health School of Medicine
News Divider
Resident physician Ashley Bartels
Ashley Bartels, MD, a resident physician in general surgery, is the lead author of a paper that won first place for a clinical science paper at a regional meeting of the American College of Surgeons’ Committee on Trauma.

Research Leads to New Test for Trauma Patients

Resident physician wins first place for clinical science paper

A test commonly used to assist in managing bleeding disorders in patients with traumatic brain injuries is unreliable, according to MU researchers.

Ashley Bartels, MD, a resident physician in general surgery at the University of Missouri, led a team of pathology, trauma surgery and neurosurgery researchers who reviewed the effectiveness of the Platelet Function Assay-100 (PFA-100) lab test for detecting platelet dysfunction in trauma patients.

“A lot of trauma patients are older and are taking aspirin or other antiplatelet agents, such as clopidogrel,” Bartels said. “Having a reliable test to detect these medications is important and helps guide our management of these patients.”

Because the medical history of trauma patients is often unknown, health care teams turn to lab tests to help them determine the best course of treatment. The PFA-100 is commonly used for trauma and neurosurgery patients.

The research group evaluated 475 cases in which PAF-100 tests were used during a 13-month period in 2013 and 2014. As a result of the study, University of Missouri Health Care started using another test, thromboelastography with platelet mapping (TEG-PM), for trauma patients instead of the PFA-100.

The team hopes to expand the study to look at the underlying mechanisms of platelet inhibition and brain injury.

Bartels was lead author of the paper that explained the researchers' findings. “Platelet Function Assay – An Unreliable Tool for Detecting Platelet Dysfunction in Traumatic Brain Injuries” won first place for a clinical science paper at a regional meeting of the American College of Surgeons’ Committee on Trauma. Bartels also presented the findings at the Central Surgical Association meeting in Chicago in March.

In addition to Bartels, the MU research team included Yaw Sarpong, MD, resident physician in neurosurgery; Jared Coberly, MD, resident physician in pathology and anatomical sciences; Natalie Hughes, medical student; N. Scott Litofsky, MD, professor of surgery and chief of the Division of Neurological Surgery; Richard Hammer, MD, associate professor of pathology and anatomical sciences; Stephen Barnes, MD, professor and chief of the Division of Acute Care Surgery; and Salman Ahmad, MD, assistant professor of surgery in the Division of Acute Care Surgery.

Posted March 25, 2015

MU Health Magazine


News and Events

David Chang Grill with Caution
Wire bristles from barbecue brushes can cause serious injuries
Tahir Rahman Extreme Beliefs Often Mistaken for Insanity, New Study Finds
Researchers say new term offers more precise definition of non-psychotic behaviors
Paul Tatum Family Medicine Professor Wins Distinguished Physician Award
Tatum recognized for outstanding care of patients near the end of life
Seth Sherman Minimally Invasive Tendon Repair Technique Supports Knee Movement Sooner after Surgery
Researchers found suture anchors, a less-invasive repair technique, responded better to strength-testing after surgery
2016 Graduation MU School of Medicine Awards 86 Medical Degrees at Commencement Ceremony
The graduates will go on to receive additional training as resident physicians in their chosen specialties
Patrice Delafontaine MU School of Medicine Dean Inducted into Prestigious Medical Society
Delafontaine joins elite group of physicians in American Clinical and Climatological Association
Steven Zweig MU Family Medicine Ranked Among Nation’s Best by U.S. News & World Report
Department has been in top 10 for 23 consecutive years
Uzma Khan MU Initiative Helps Rural Doctors Treat Chronic Pain
Show-Me ECHO to offer special training session April 28
Legacy Teachers MU School of Medicine Program Expands to Other Medical Schools
MU’s Legacy Teachers program lets students recognize patients as educators
Susan Nagel Oil and Gas Wastewater Disposal May Increase Endocrine Disrupting Activity
Scientists draw conclusions after study at natural gas and oil extraction wastewater disposal facility
St. Baldricks 2016 Participants Go Bald for Childhood Cancer Research
Community donates more than $40,000 to the cause

Media Relations
University of Missouri Health System
One Hospital Drive, DC028.00
Columbia, MO 65212
24/7 on-call pager: (573) 876-0708

Mary Jenkins
(573) 882-7299

Jeff Hoelscher
(573) 884-1608

Derek Thompson
(573) 882-3323

Diamond Dixon
(573) 884-7541

Justin Kelley (Photographer)
(573) 882-5786
Pager (573) 397-9289

Web Communications
University of Missouri Health System
One Hospital Drive, MA204G, DC018.00
Columbia, MO 65212
(573) 884-0298

Jennifer Orford
(573) 882-0298

Deidra Ashley
(573) 884-3988

Jesslyn Chew
(573) 884-2891

Velvet Hasner
(573) 884-1115

Justin Willett
(573) 884-7740

Printer Friendly
Follow us on Twitter!   Facebook   YouTube Videos   Instagram   Pinterest  
Website created and maintained by the Office of Communications. Contact the MU School of Medicine.
Revised: March 25, 2015 - Copyright © 2014 - Curators of the University of Missouri. All rights reserved. DMCA and other copyright information. An equal opportunity/access/affirmative action/pro-disabled and veteran employer.