University of Missouri School of Medicine MU Health School of Medicine
Orthopaedic Surgery Divider
General Oncology Foot & Ankle Hand Hip & Knee Pediatrics Spine Sports Medicine Trauma

MOI Missouri

Missouri Orthopaedic Institute





Research Projects

Ajay Aggarwal, MD
Exploratory evaluation of the potential for long-term retention of Gadolinium in the bones of patients who have received Gadolinium based contrast agents according to their medical history
Funding: Ecron Acunova

Restoration® Anatomic Dual Mobility (ADM) X3® Acetabular System Study with Long Term Data Collection for the Accolade® II Hip Stem Outcomes Study
Funding: Stryker


Tom Aleto, MD
A Prospective Non-Controlled Study on Signature Posterior/Lateral Acetabular Cup Placement System in Total Hip Arthroplasty
Funding: Biomet

A Global Comparison of Signature™ Guides and Traditional Instruments in the Oxford™ Partial Knee
Funding: Biomet


B. Sonny Bal, MD, JD, MBA
Outcomes Following Anterior Approach to Total Hip Arthroplasty: A Multi-Centre Observational Cohort Study
Funding: McMaster University

CT-navigated, patient-specific custom total knee replacement versus standard total knee replacement: Comparison with a Marker-less Gait Analysis System and Validated Outcome Scores
Funding: None

Ted Choma, MD
Analysis of Pedicle Screw Performance in Osteoporotic Bone: Phase I -- Biomechanical Testing and Finite Element Analysis of in vitro Samples
Funding: Stryker Spine

Evaluation of the Effects of Tapping Depth on Pedicle Screw Fixation Strength in Non and Cement Augmented Human Pedicles
Funding: Stryker Spine

Assessment of Collecting Patient Outcomes with a Computer-Based Program versus Paper Questionnaires
Funding: AO Foundation


James L. Cook, DVM, PhD
Clinical Pilot Study examining Nutramax Nutraceuticals for treatment of knee osteoarthritis
Funding: Nutramax


Brett Crist, MD
Hemostasis in open acetabulum and pelvic ring surgery using tranexamic acid: a prospective, randomized, controlled study
Funding: Orthopaedic Trauma Association

Antibiotic Prophylaxis in Orthopaedic Traumatology: A Prospective, Randomized Trial of Duration of Administration
Funding: Orthopaedic Trauma Association

Management of Complex Wounds Using a Constant Tension External Tissue Expander
Funding: Wound Care Tech, Inc.

Multicenter Prospective Cohort Study: Operative and Non-Operative Treatment for Extraarticular Scapula Fractures
Funding: University of Minnesota

Patient Outcome Comparison of Intramedullary Locked Nailing vs Non-operative Management of Extra-articular and Minimally Displaced Intra-articular Distal Radius Fractures in the Elderly
Funding: Sonoma Orthopedic Products Inc.

Lateral versus Anterior Spanning External Fixator for Tibial Plateau Fractures
Funding: None

Direct Anterior versus Posterior Surgical Approaches for Total Hip Arthroplasty: A Comparison Functional Outcomes Utilizing a Markerless Gait Analysis System and Validated Outcome Scores
Funding: None

Role of Vacuum Assisted Closure (VAC) Device in Postoperative Management of Pelvic and Acetabular Fractures
Funding: None

Review of Anterolateral versus Anteromedial Approaches of the Ankle for Pilon Fractures
Funding: None

A Multi-center Trial of the Role of Vacuum Assisted Closure (VAC) Device in Postoperative Management of Pelvic, Acetabular, and Hip Fractures
Funding: None

Functional Outcomes of Patients Undergoing Anterolateral versus Anteromedial Approaches of the Ankle for Pilon Fractures
Funding: None

Comparison of Submusclular Bridge Plating vs. Non-Operative Casting and Immobilization in Treatment of Pediatric Tibia Fractures
Funding: None

Incidence of Ankle Fusion After Pilon Fracture
Funding: None

Olecranon Osteotomy Fixation with a Pre-contoured Plate
Funding: None

Incidence of Knee Arthroplasty after Tibial Plateau Fractures
Funding: None


Gregory Della Rocca, MD, PhD
Integrin signaling and hyaline cartilage response to blunt trauma
Funding: Orthopaedic Trauma Association

Standard Reaming versus Reaming/ Irrigating/ Aspirating for Intramedullary Nailing of Femoral Shaft Fractures (STAFF)
Funding: Greenville Hospital System

Fluid Lavage of Open Wounds (FLOW): A Multi-Center, Blinded, Factorial Trial Comparing Alternative Irrigating Solutions and Pressures in Patients with Open Fractures
Funding: Greenville Hospital System

Trial to Evaluate Ultrasound in the Treatment of Tibial Fractures (TRUST)
Funding: McMaster University

Effect of hip fracture management protocols on patient outcomes in a geriatric hip fracture population
Funding: Orthopaedic Trauma Association

PRAISE: Prevalence of Abuse and Intimate Partner Violence Surgical Evaluation
Funding: McMaster University

Closure of Fasciotomy Wounds: A Prospective, Cohort Study of Two Different Wound Closure Techniques
Funding: Wound Care Tech, Inc.

A Multicenter Prospective Cohort Study of Sacral Fractures Using Patient Based and Objective Outcomes
Funding: University of Minnesota

Fixation using Alternative Implants for the Treatment of Hip Fractures (FAITH)
Funding: University of Minnesota

Establishing a Prospective Database of Patient Clinical Visits Utilizing Survey Outcome Measurements
Funding: McMaster University

Clinical Outcomes of Talus Fractures
Funding: None

Complex Periarticular Fracture-Dislocation of the Elbow: a Retrospective Review
Funding: None

Outcomes of Open Distal Femur Fractures Compared to Closed Distal Femur Fractures? A Retrospective Medical Record Review
Funding: None

A Multi-Center Randomized Controlled Pilot Study of Dynamic Locking Screws 5.0 vs. Standard Locking Screws in Fracture of Distal Femur Treated with Locked Plate Fixation
Funding: AO Foundation


Aaron Gray, MD
Validation of an inexpensive motion analysis device for evaluation athletes at risk of an anterior cruciate ligament rupture
Funding: None

Study of video game intervention for ankle rehabilitation
Funding: None

The biomechanical components of the youth baseball pitching motion
Funding: None

The biomechanics of ballet using a markerless motion analysis system: a comparison of dancers on flat and en pointe
Funding: None


Daniel Hoernschemeyer, MD
Vertical Expandable Prosthetic Titanium Rib (VEPTR) (HO30009)
Funding: None


Joel Jeffries, MD
Distribution of Injectable after Interlaminar Epidural Steroid Injections in the Cervical & Lumbar Spine Evaluated with CT Imaging
Funding: None

Effect of iPad use on the surgical resident education: A Pilot Study
Funding: None


Tom Reinsel, MD
A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy Safety, and Pharmacokinetics of SUN13837 Injection in Adult Subjects with Acute Spinal Cord Injury (ASBI)
Funding: Asubio pharmaceuticals


Seth Sherman, MD
The Effects of Core Weakness on Knee Kinematics, Response to Injury, and Recovery from Surgery
Funding: none

Overutilization of MRI if the Diagnosis and Treatment of Moderate to Severe Osteoarthritis
Funding: None


Matthew J. Smith, MD
Safety and Effectiveness of the Simpliciti System in Replacing the humeral Head in Total Shoulder Arthroplasty
Funding: Tornier

A Bone-Tendon Allograft System Optimizing Tissue Healing and Biomechanical Strength for Human Rotator Cuff Repair (Co-Principal Investigator with Ferris Pfeiffer, PhD)
Funding: Walter H. Coulter Foundation

Incidence of Vitamin D Deficiency in Missouri Trauma Patients Treated for a Fracture
Funding: None

Evaluation of Pathologic cell Signaling in Osteoarthritis of the Shoulder
Funding: None

A Retrospective Five Year Review of Plain Shoulder Radiographs Treated with Reverse TSA
Funding: None

Establishing a Prospective Database of Patient Clinical Visits Utilizing Survey Outcome Measurements
Funding: None


James Stannard, MD
Clinical Priority Program: Cone Infection Registry. Implementation of a Registry on Bone Infection to Improve Patient Outcomes and Research Efforts
Funding: AO Foundation

A Prospective, randomized investigation of syndesmosis injury fixation (TightRope)
Funding: Arthrex Inc.

A prospective, randomized, controlled clinical study to assess the prevention of postsurgical incision healing complications in patients undergoing primary or revision Total Knee Arthroplasty (TKA) or Total Hip Arthroplasty (THA), treated with either Single-Use Negative Pressure Wound Therapy (NPWT) or standard postsurgical dressings
Funding: Smith & Nephew

A Modified Osteochondral Allograft System, Focused on Improving the Efficacy of Osteochondral Allografts (Co-Principal Investigator with Ferris Pfeiffer, PhD)
Funding: Walter H. Coulter Foundation

Comparison of Diagnostic Modalities for Meniscal Pathology
Funding: None

Safety and Effectiveness of a Novel Articular Cartilage Graft Preservation System: a Pilot Study
Funding: None

Multiligament Knee Reconstruction: Functional and Clinical Outcomes
Funding: None

Functional motion analysis of MU intramural and club athletes using the DARI Marker-less Motion Capture Device
Funding: None

In Vivo Assessment of the Osteoinductive Potential of Reamer Irrigator Aspirator (RIA) "waste Water" Proteins
Funding: None


David Volgas, MD
Double Blinded, Randomized Clinical Trial of the Twin Star ECSPRESS Monitoring system for the Reduction of the Incidence of Fasciotomy
Funding: Twin Star Medical Inc.

Are routine post-operative radiographs necessary after fixation of periarticular fractures?
Funding: None


Richard White, MD
Technology for Producing Superior ACL Grafts by Conjugating Nanomaterials with Acellular Biologically Derived Tissue (Co-Principal Investigator with Sheila Grant, PhD)
Funding: Walter H. Coulter Foundation

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