Profile
Through the Thompson Laboratory for Regenerative Orthopaedics, Dr. Bozynski's team's research focuses on orthopedic disorders of diarthrodial joints. She is the principal investigator on a study to develop a reliable panel of protein biomarkers in serum and urine with high discriminatory capability for early diagnosis of hip dysplasia in skeletally immature dogs. Based on her extensive experience in histopathology of synovium, meniscus, tendons, ligaments, fat pad, intervertebral discs, articular cartilage, and bone, she is responsible for examination of all study tissues. Her main roles are to (i) quantify and characterize microarchitectural changes seen in joint tissues of the limbs and intervertebral disc for in vivo, ex vivo and in vitro studies, (ii) develop and validate biomarkers of osteoarthritis in synovial fluid, serum, and urine, and (iii) validate canine models of osteoarthritis.
Academic Information
Office
1100 Virginia Avenue
Columbia, MO 65212
United States
Research Interests
- Orthopaedic disorders of diarthrodial joints
Areas of Expertise
- Osteoarthritis
- Intervertebral disc disease
- Biomarkers of hip dysplasia
- Histopathology of orthopaedic disease
- Anatomic Pathology (board-certified)
Education & Training
Residency
University of Missouri, 2010
Post-Graduate School
Universite de Montreal, 2006
Master’s
University of British Columbia, Vancouver, Canada M.Sc. in Zoology
Awards & Honors
- Board certified by the American College of Veterinary Pathologists, 2011
- C.L. Davis Foundation Student Scholarship Award, 2010
- ACVP Young Investigator Award (1st place), 2009
Publications
Selected from more than 30 peer-reviewed publications:
- Ahner CE, Stoker AM, Bozynski CC, Cook CR, Leary E, Kuroki K, Cruz CN, Cook JL. 2019. Protein biomarkers in serum and urine for determining presence or absence of hip dysplasia in a canine model. Journal of Orthopaedic Research 37:916-920
- Kuroki K, Williams N, Ikeda H, Bozynski CC, Leary E, Cook JL. 2019. Histologic evaluation of ligament vascularity and synovitis in dogs with cranial cruciate ligament disease. American Journal of Veterinary Research 80:152-158
- Smith PA, Bozynski CC, Kuroki K, Henrich SM, Wijdicks CA, Cook JL. 2018. Intra-articular biocompatibility of multistranded, long-chain polyethylene suture tape in a canine ACL model. Journal of Knee Surgery May 31 (Epub ahead of print)
- Brimmo OA, Bozynski CC, Cook CR, Kuroki K, Sherman SL, Pfeiffer FM, Stoker AM, Cook JL. 2018. Subchondroplasty for the treatment of post-traumatic bone marrow lesions of the medial femoral condyle in a pre-clinical canine model. Journal of Orthopaedic Research 36:2709-2717
- Stoker AM, Stannard JP, Kuroki K, Bozynski CC, Pfeiffer FM, Cook JL. 2018. Validation of the Missouri Osteochondral Allograft Preservation Systems for the maintenance of osteochondral allograft quality during prolonged storage. The American Journal of Sports Medicine 46:58-65
- Franklin SP, Stoker AM, Bozynski CC, Kuroki K, Clarke KM, Johnson JK, Cook JL. 2018. Comparison of platelet-rich plasma, stromal vascular fraction (SVF), or SVF with an injectable PLGA nanofiber scaffold for the treatment of osteochondral injury in dogs. Journal of Knee Surgery 31:686-697
- Ravanfar M, Pfeiffer FM, Bozynski CC, Wang Y, Yao G. 2017. Parametric imaging of collagen structural changes in human osteoarthritic cartilage using optical polarization tractography. Journal of Biomedical Optics 22:1-10
- Cook JL, Stannard JP, Stoker AM, Bozynski CC, Kuroki K, Cook CR, Pfeiffer FM. 2016. Importance of donor chondrocyte viability for osteochondral allografts. The American Journal of Sports Medicine 44:1260-1268
- Bozynski CC, Stannard JP, Smith PA, Hanypsiak B, Kuroki K, Stoker AM, Cook CR, Cook JL. 2016. Acute management of ACL injuries using novel canine models. Journal of Knee Surgery 29:594-603
- Bozynski CC, Kuroki K, Stannard JP, Smith PA, Stoker AM, Cook CR, Cook JL. 2015. Evaluation of partial transection versus synovial debridement of the ACL as novel canine models for management of ACL injuries. Journal of Knee Surgery 28:404-410