Karen Bennett, PhD


Developmental and molecular biology of nematodes, Ascaris suum, Caenorhabditis elegans, and Ascaris lumbricoides.

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Academic Information

Professor Emerita
P. 573-882-8152

Areas of Expertise

Molecular Genetics

Education & Training

Post-Graduate School

1983, PhD, State University of New York at Buffalo


  1. McEwen, TJ, Yao, Q, Yun, S and KL Bennett.  2016.  Small RNA in situ hybridization in Caenorhabditis elegans, combined with RNA-seq, identifies germline-enriched microRNAs.  Dev Bio 2016 Oct 15, 418(2):248-257.   PMID: 27521456, PMCID: PMC5131644  DOI: 10.1016/j.ydbio.2016.08.003
  2. Gao, G, Deeb, F, Mercurio, JM, Parfenova, A, Smith, PA and KL Bennett.  2012.  PAN-1, a P-granule component important for C. elegansfertility, has dual roles in the germline and soma.  Develomental Biology 364:202-213.
  3. Beshore, Erica L., Tamara J. McEwen, Molly C. Jud, Jordan K. Marshall, Jennifer A. Schisa and Karen L. Bennett. 2011. C. elegans Dicer interacts with the P-granule component GLH-1 and both regulate germline RNPs. Developmental Biology 350:370-381.
  4. van der Voet, Monique, Lorson, Monique A., Srinivasan, Dayalan G., Bennett, Karen L. and Sander van den Heuvel. 2009. C. elegans mitotic cyclins have distinct as well as overlapping functions in chromosome segregation. Cell Cycle 8(24):4091-102.
  5. Spike, Caroline, Nicole Meyer, Erica Racen, April Orsborn, Jay Kirchner, Kathleen Kuznicki, Christopher Yee, Karen Bennett and Susan Strome. 2008. Genetic Analysis of the C. elegans GLH family of P-granule proteins. Genetics 178(4):1973-1987.
  6. Orsborn, A.M., W. Li, t. McEwen, T. Mizuno, E. Kuzmin, K. Matsumoto, and K.L. Bennett. 2007. GLH-1, the C. elegans, P granule protein, is controlled by KGB-1 and by the COP9 subunit CSN-5. Development 134:3383-3392.
  7. Li, W, B Gao, S-M Lee, K. Bennett, and D. Fang. 2007. RLE-1, a novel E3 ubiquitin ligase, regulates C. elegans aging by catalyzing DAF-16 polyubiquitination. Developmental Cell 12:235-246.
  8. Gao, Ge, Sheela Raikar, Bianca Davenport, Lejla Mutapcic, Ruth Montgomery, Eugene Kuzmin and Karen L. Bennett. 2006. Cross-species RNAi: Selected Ascaris suum dsRNAs can sterilize Caenorhabditis elegans. Molecular and Biochemical Parasitology 146:124-128.
  9. Momoyo Hanazawa, Ichiro Kawasaki, Hirofumi Kunitomo, Keiko Gengyo-Ando, Karen L. Bennett, Shohei Mitani, Yuichi Iino. 2004. TheCaenorhabditis elegans eukaryotic initiation facto 5A homologue, IFF-1, is required for germ cell proliferation, gametogenesis and localization of the P-granule component PGL-1. Mechanisms of Development 121: 213-224.
  10. Smith, Pliny, W-M Leung-Chiu, Ruth Montgomery, April Orsborn, Kathleen Kuznicki, Emily Gressman-Coberly, Lejla Mutapcic, and Karen Bennett. 2002. The GLH Proteins, Caenorhabditis elegans P Granule components, Associate with CSN-5 and KGB-1, Proteins Necessary for Fertility, and with ZYX-1, a Predicted Cytoskeletal Protein. Developmental Biology. 251:333-347. Chosen by the Faculty of 1000 as a 2002 paper.
  11. Kuznicki KA, Smith PA, Leung-Chiu WMA, Estevez AO, Scott HC, Bennett, KL. 2000. Combinatorial RNA interference indicates GLH-4 can compensate for GLH-1; these two P granule components are critical for fertility in C. elegans. Development. 127:2907-2916.
  12. Gruidl, M.E., P.A. Smith, K.A. Kuznicki, J.S. McCrone, J. Kirchner, D.L. Roussell, S. Strome and K.L. Bennett. 1996. Multiple potential germline helicases, GLHs, are components of the germline-specific P granules of Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA. 93:13837-13842.
  13. Roussell, D.L., M.Gruidl and K.L. Bennett. 1994. Germ-line determination in Caenorhabditis and Ascaris: Will a Helicase begin to unravel the mystery? Parasitology Today. 103:110-113.
  14. Roussell, D.L. and K.L. Bennett. 1993. glh-1: a Germline Putative RNA Helicase from Caenorhabditis has Four Zinc Fingers. Proc. Natl. Acad. Sci, USA. 90:9300-9304.