Lakshmi Pulakat, M.Phil, PhD

Profile

The core focus of Dr. Pulakat’s research is the elucidation and manipulation of various biological pathways that contribute to the development and pathogenesis of cardio-metabolic disease. Dr. Pulakat is involved in various projects focused on developing technologies and devices to enable better delivery of drugs for both research and clinical purposes. Her research has evolved over the past decade from utilizing classic molecular biology and biotechnology methods in basic science research to working on highly translational research focused on validation and testing of new therapeutics and devices as well as identifying key therapeutic targets. Her current research includes extensive collaboration with small business interests (primarily Novopyxis Inc, and Droplette Inc., both Boston-based biotechnology companies) and clinicians at Tufts Medical Center and UM-Columbia. Dr. Pulakat’s NIH-funded research is focused on characterizing a new cardiomyopathy drug to treat diabetes- and chemotherapy-induced cardiovascular toxicity, and identifying sex differences in development of these pathologies and the drug responses. Dr. Pulakat is also involved in the development of a new treatment for chronic wounds such as venous stasis, diabetic ulcers and pressure ulcers using a transdermal delivery system capable of delivering gene and protein therapy to expedite wound healing.

Academic Information

Professor

Office

1 Hospital Dr
Columbia, MO 65212
United States

P. 573-814-6000

Research Interests

  • Cardiovascular Disease
  • Diabetes & Metabolism

Areas of Expertise

  • Cardiovascular disease
  • Diabetes
  • Obesity
  • Chronic wound healing
  • Molecular pathways
  • Drug development
  • Transdermal delivery

Education & Training

Fellowship

1993, Signal Transduction, Department of Neurobiology and Behavior (Psychobiology), University of California, Irvine, California

Post-Graduate School

1989, Ph.D., Biochemistry and Molecular Biology, Russel Grimwade School of Biochemistry, University of Melbourne, Australia; 1984, M.Phil., Molecular Biology, DST Unit of Genetic Engineering, Jawaharlal Nehru University, India; 1981, M.Sc., Life Sciences,

Awards & Honors

  • 2012-13: Excellence in Education Award, University of Missouri-Columbia Division of Student Affairs
  • 2008: Invited Speaker, Angiotensin Gordon Research Conference
  • 2010: Presenter, Angiotensin Gordon Research conference
  • 2008: Featured speaker, College of Arts and Sciences Research Showcase, MSU
  • 2006: National Siemens Competition Mentor
  • 2004: Recipient of 2004 President’s Award for Collaborative Research/Creative Work with Graduate Students (Bowling Green State University)
  • 2004: Certificate of Appreciation from The Distinguished Thesis Award Committee for Mentoring (Bowling Green State University)
  • 2001: Certificate of Appreciation from The Distinguished Dissertation Award Committee for Mentoring (Bowling Green State University)
  • 2000: Recipient of 2000 Elliot L. Blinn Award for Faculty-Undergraduate Student Innovative Basic Research/Creative Work (Bowling Green State University)
  • 1999: Outstanding Contributor to the Graduate Education (Graduate Student Senate, Bowling Green State University)
  • 1999: Invited Speaker, The Ohio Physiological Society 14th Annual Meeting, Miami University, Oxford, Ohio
  • 1998 - present: Elected Fellow of Ohio Academy of Sciences
  • 1996: Department of Biological Sciences Teaching Award (for Superior Performance in Teaching), Bowling Green State University, April 1996.
  • 1985 - 1988: University of Melbourne Post graduate Scholarship, Melbourne, Australia.
  • 1976 - 1984: National Science Talent Scholarship awarded by the National Council of Educational Research and Training (N.C.E.R.T.), India.
  • 1981: First rank in National level entrance examination for M.Phil. Admission in the School of Environmental Sciences, Jawaharlal Nehru University, New Delhi, India.

Professional Societies

  • American Heart Association
  • High Blood Pressure Research Council
  • American Society for Biochemistry and Molecular Biology
  • American Society for Microbiology
  • American Association for Advancement of Science
  • Ohio Academy of Sciences, elected felow
  • Felow, Institute of Neurocognitive Science and Technology, MSU
  • American Heart Association Greater Southeast Affiliate Region II Molecular Signaling Review committee member (2008 - present)