Wenjun Ma, PhD

Wenjun Ma, PhD

Department of Veterinary Pathobiology

Molecular Microbiology and Immunology

Associate Professor Veterinary Pathobiology
Associate Professor Molecular Microbiology & Immunology

573-882-2863

Profile

Dr. Ma’s research interests include viral diseases of animals, with an emphasis on emerging zoonotic viral infections. His current research focuses on understanding mechanisms of pathogenesis and transmissibility, virus-host interaction and developing vaccines and antivirals for different zoonotic viral pathogens, such as Influenza virus, Rift Valley fever virus and other viral infections. He is also interested in development of rapid detection systems for viral diseases. Dr. Ma’s long-term goals are to apply molecular biology and virology approaches to generate countermeasures and scientific knowledge that can be used to address current challenge from influenza and other important diseases for industry and public health needs.

Academic Information

Associate Professor Veterinary Pathobiology
Associate Professor Molecular Microbiology & Immunology

Office

W118 Veterinary Medicine Bldg
Columbia, MO 65211
United States

P. 573-882-2863

Research Interests

  • Influenza
  • Rift Valley fever
  • Virology
  • Zoonotic viral disease
  • Virus-host interaction
  • Vaccine
  • Antiviral
  • Animal model
  • Bat-derived viruses

Areas of Expertise

  • Influenza
  • Rift Valley fever
  • Virology
  • Microbiology
  • Vaccine
  • Antiviral
  • Animal model

Education & Training

Fellowship

2008, Iowa State University and National Animal Disease Center, USDA/ARS, Iowa, USA

Post-Graduate School

2003, PhD, Justus-Liebig-University, Giessen, Germany

Awards & Honors

  • 2019 Zoetis Animal Health Award for Research Excellence, College of Veterinary Medicine, Kansas State University

Publications

A full list of publications: W Ma publications

Ciminski K, Ran W, Gorka M, Lee J, Malmlov A, Schinköthe J, Eckley M, Murrieta RA, Aboellail TA, Campbell CL, Ebel GD, Ma J, Pohlmann A, Franzke K, Ulrich R, Hoffmann D, García-Sastre A, Ma W, Schountz T, Beer M, Schwemmle M. Bat influenza viruses transmit among bats but are poorly adapted to non-bat species. Nat Microbiol. 2019 Dec;4(12):2298-2309.

Lee J, Wang L, Palinski R, Walsh T, He D, Li Y, Wu R, Lang Y, Sunwoo SY, Richt JA, Ma W. Comparison of Pathogenicity and Transmissibility of Influenza B and D Viruses in Pigs. Viruses. 2019 Sep 27;11(10).

Wang R, Zhu Y, Lin X, Ren C, Zhao J, Wang F, Gao X, Xiao R, Zhao L, Chen H, Jin M, Ma W, Zhou H. Influenza M2 protein regulates MAVS-mediated signaling pathway through interacting with MAVS and increasing ROS production. Autophagy. 2019 Jul;15(7):1163-1181.

Ma J, Shen H, McDowell C, Liu Q, Duff M, Lee J, Lang Y, Hesse D, Richt JA, Ma W. Virus survival and fitness when multiple genotypes and subtypes of influenza A viruses exist and circulate in swine. Virology. 2019 Apr 9;532:30-38.

Lang Y, Li Y, Jasperson D, Henningson J, Lee J, Ma J, Li Y, Duff M, Liu H, Bai D, McVey S, Richt JA, Ikegami T, Wilson WC, Ma W. Identification and evaluation of antivirals for Rift Valley fever virus. Vet Microbiol. 2019 Mar;230:110-116.

Sunwoo SY, Pérez-Núñez D, Morozov I, Sánchez EG, Gaudreault NN, Trujillo JD, Mur L, Nogal M, Madden D, Urbaniak K, Kim IJ, Ma W, Revilla Y, Richt JA. DNA-protein vaccination strategy does not protect from challenge with African swine fever virus Armenia 2007 strain. Vaccines (Basel). 2019 Jan 28;7(1).

Endalew AD, Morozov I, Davis AS, Gaudreault NN, Wernike K, Bawa B, Ruder MG, Drolet BS, McVey DS, Shivanna V, Ma W, Faburay B, Wilson WC, Richt JA. Virological and Serological Responses of Sheep and Cattle to Experimental Schmallenberg Virus Infection. Vector Borne Zoonotic Dis. 2018 Dec;18(12):697-703.

Sunwoo SY, Schotsaert M, Morozov I, Davis AS, Li Y, Lee J, McDowell C, Meade P, Nachbagauer R, García-Sastre A, Ma W, Krammer F, Richt JA. A Universal Influenza Virus Vaccine Candidate Tested in a Pig Vaccination-Infection Model in the Presence of Maternal Antibodies. Vaccines (Basel). 2018 Sep 14;6(3).

Yan D, Shi Y, Wang H, Li G, Li X, Wang B, Su X, Wang J, Teng Q, Yang J, Chen H, Liu Q, Ma W, Li Z. A Single Mutation at Position 156 in the Envelope Protein of Tembusu Virus Is Responsible for Virus Tissue Tropism and Transmissibility in Ducks. J Virol. 2018 Sep 1;92(17).

Ma J, Lee J, Liu H, Mena I, Davis AS, Sunwoo SY, Lang Y, Duff M, Morozov I, Li Y, Yang J, García-Sastre A, Richt JA, Ma W. Newcastle disease virus-based H5 influenza vaccine protects chickens from lethal challenge with a highly pathogenic H5N2 avian influenza virus. NPJ Vaccines. 2017;2:33.

Wang D, Ma W. Visualization of IAV Genomes at the Single-Cell Level. Trends Microbiol. 2017 Oct;25(10):781-782.

Yang J, Lee J, Ma J, Lang Y, Nietfeld J, Li Y, Duff M, Li Y, Yang Y, Liu H, Zhou B, Wentworth DE, Richt JA, Li Z, Ma W. Pathogenicity of modified bat influenza virus with different M genes and its reassortment potential with swine influenza A virus. J Gen Virol. 2017 Apr;98(4):577-584.

Lee J, Yu H, Li Y, Ma J, Lang Y, Duff M, Henningson J, Liu Q, Li Y, Nagy A, Bawa B, Li Z, Tong G, Richt JA, Ma W. Impacts of different expressions of PA-X protein on 2009 pandemic H1N1 virus replication, pathogenicity and host immune responses. Virology. 2017 Apr;504:25-35.

Lang Y, Henningson J, Jasperson D, Li Y, Lee J, Ma J, Li Y, Cao N, Liu H, Wilson W, Richt J, Ruder M, McVey S, Ma W. Mouse model for the Rift Valley fever virus MP12 strain infection. Vet Microbiol. 2016 Nov 15;195:70-77.

Faburay B, Wilson WC, Gaudreault NN, Davis AS, Shivanna V, Bawa B, Sunwoo SY, Ma W, Drolet BS, Morozov I, McVey DS, Richt JA. A Recombinant Rift Valley Fever Virus Glycoprotein Subunit Vaccine Confers Full Protection against Rift Valley Fever Challenge in Sheep. Sci Rep. 2016 Jun 14;6:27719.