Laurin Hanft, PhD

Academic Information

Assistant Teaching Professor


MA415 Medical Science Bldg
Columbia, MO 65212
United States

P. 573-882-8267

Research Interests

  • Striated muscle function and regulation in health and disease

Areas of Expertise

  • Teaching systems physiology at the University of Missouri
  • Mechanical and biophysical measurements of force development, rates of force development, and power output in striated muscle cells
  • Whole heart function utilizing working heart preparations
  • Biochemical techniques including: 1-dimensional and 2-dimensional gel electrophoresis, western blotting, autoradiograms, confocal microscopy, protein purification, and generation of monoclonal and polyclonal antibodies

Education & Training


University of Missouri

Post-Graduate School

2005, PhD, University of Wisconsin-Madison

Awards & Honors

  • Student Travel Award, American Society for Cell Biology
  • 1st Place Poster Award, Myofilament Meeting, Madison, WI
  • 1st place award for talk at Early Career Investigator Symposium, Myofilament Meeting, Madison, WI.
  • Member of the Biophysical Society
  • Fellow of the American Heart Association


  • McDonald KS, Hanft LM, Robinett JC, Guglin M, Campbell KS.
    Regulation of Myofilament Contractile Function in Human Donor and Failing Hearts.
    Front Physiol. 2020;11:468. doi: 10.3389/fphys.2020.00468. eCollection 2020. PubMed PMID: 32523542; PubMed Central PMCID: PMC7261867.
  • Robinett JC, Hanft LM, Geist J, Kontrogianni-Konstantopoulos A, McDonald KS.
    Regulation of myofilament force and loaded shortening by skeletal myosin binding protein C.
    J Gen Physiol. 2019 May 6;151(5):645-659. doi: 10.1085/jgp.201812200. Epub 2019 Jan 31. PubMed PMID: 30705121; PubMed Central PMCID: PMC6504288.
  • Hanft LM, McDonald KS. Regulating myofilament power:
    The determinant of health.
    Arch Biochem Biophys. 2019 Mar 15;663:160-164. doi: 10.1016/ Epub 2019 Jan 10. Review. PubMed PMID: 30639328.
  • Hanft LM, Emter CA, McDonald KS.
    Cardiac myofibrillar contractile properties during the progression from hypertension to decompensated heart failure.
    Am J Physiol Heart Circ Physiol. 2017 Jul 1;313(1):H103-H113. doi: 10.1152/ajpheart.00069.2017. Epub 2017 Apr 28. PubMed PMID: 28455288; PubMed Central PMCID: PMC5538866.
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