Academic Information
Assistant Teaching Professor
Office
MA415 Medical Science Bldg
Columbia, MO 65212
United States
P. 573-882-8267
Research Interests
- Striated muscle function and regulation in health and disease
Areas of Expertise
- Teaching systems physiology at the University of Missouri
- Mechanical and biophysical measurements of force development, rates of force development, and power output in striated muscle cells
- Whole heart function utilizing working heart preparations
- Biochemical techniques including: 1-dimensional and 2-dimensional gel electrophoresis, western blotting, autoradiograms, confocal microscopy, protein purification, and generation of monoclonal and polyclonal antibodies
Education & Training
Fellowship
University of Missouri
Post-Graduate School
2005, PhD, University of Wisconsin-Madison
Awards & Honors
- Student Travel Award, American Society for Cell Biology
- 1st Place Poster Award, Myofilament Meeting, Madison, WI
- 1st place award for talk at Early Career Investigator Symposium, Myofilament Meeting, Madison, WI.
- Member of the Biophysical Society
- Fellow of the American Heart Association
Publications
- McDonald KS, Hanft LM, Robinett JC, Guglin M, Campbell KS.
Regulation of Myofilament Contractile Function in Human Donor and Failing Hearts.
Front Physiol. 2020;11:468. doi: 10.3389/fphys.2020.00468. eCollection 2020. PubMed PMID: 32523542; PubMed Central PMCID: PMC7261867. - Robinett JC, Hanft LM, Geist J, Kontrogianni-Konstantopoulos A, McDonald KS.
Regulation of myofilament force and loaded shortening by skeletal myosin binding protein C.
J Gen Physiol. 2019 May 6;151(5):645-659. doi: 10.1085/jgp.201812200. Epub 2019 Jan 31. PubMed PMID: 30705121; PubMed Central PMCID: PMC6504288. - Hanft LM, McDonald KS. Regulating myofilament power:
The determinant of health.
Arch Biochem Biophys. 2019 Mar 15;663:160-164. doi: 10.1016/j.abb.2019.01.008. Epub 2019 Jan 10. Review. PubMed PMID: 30639328. - Hanft LM, Emter CA, McDonald KS.
Cardiac myofibrillar contractile properties during the progression from hypertension to decompensated heart failure.
Am J Physiol Heart Circ Physiol. 2017 Jul 1;313(1):H103-H113. doi: 10.1152/ajpheart.00069.2017. Epub 2017 Apr 28. PubMed PMID: 28455288; PubMed Central PMCID: PMC5538866.
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