Olga Glinskii, MD

Olga Glinskii, MD
Assistant Research Professor
VA Research Investigator, Harry S. Truman Memorial Veterans Hospital

573-882-4625

Academic Information

Assistant Research Professor
VA Research Investigator, Harry S. Truman Memorial Veterans Hospital

Office

1 Hospital Dr
MA415 Medical Science Bldg.
Columbia, MO 65212
United States

P. 573-882-4625

Research Interests

  • Estrogen-dependent microvascular remodeling in pathogenesis of intracranial disorders
  • Microvascular pathophysiology of hematogenous cancer metastasis

Areas of Expertise

  • Meningeal microvascular remodeling
  • Fluorescence, confocal, ex vivo, and real time microscopy with video imaging and analysis
  • Computerized quantitative image analysis
  • Microdissection and microsurgery
  • Metastasis-associated carbohydrate-mediated endothelial activation
  • Molecular and biochemical processes supporting cancer/endothelial cells interaction, arrest, and retention
  • Biochemical, cell biology and immunological techniques
  • Cell culture
  • Flow chamber models

Awards & Honors

  • 2008-2011 American Heart Association, Scientist Development Grant (National Center Research Program)
  • 2005-2007 American Heart Association Postdoctoral Fellowship. Heartland Affiliate
  • 2002-2005 NIH Ruth L. Kirschstein National Research Service Award (NRSA)
  • 1993 Internal Medicine Category I Award, Ukrainian Ministry of Public Health, Kiev, Ukraine

Publications

  • Glinskii, O.V., Sud S., Mossine V.V., Mawhinney T.P., Anthony D.C., Glinsky G.V., PientaK.J., and Glinsky V.V.
  • Inhibition of Prostate Cancer Bone Metastasis by Synthetic TF Antigen Mimic/Galectin-3 Inhibitor Lactulose-L-Leucine. Neoplasia, 14:65-73, 2012.
  • Glinskii OV, Huxley VH, Glinskii VV, Rubin LJ, Glinsky VV (2013) Pulsed Estrogen Therapy Prevents Post-OVX Porcine Dura. Mater Microvascular Network Weakening via a PDGF-BB-Dependent Mechanism. PLoS ONE 8(12): e82900. doi:10.1371/journal.pone.0082900
  • Prasath V.S., Bunyak F., Haddad O., Glinskii O., Glinsky V., Huxley V., Palaniappan K. Robust Filtering based Segmentation and Analysis of Dura Mater Vasculature using Epifluorescent Microscopy. 35th IEEE EMBS, 2013:6055-6058
  • Glinskii OV, Li F, Wilson LS, Barnes S, Rittenhouse-Olson K, Barchi JJ Jr., Pienta KJ, Glinsky VV. Endothelial integrin a3b1 stabilizes carbohydrate-mediated tumor/endothelial cell adhesion and induces macromolecular signaling complex formation at the endothelial cell membrane. Oncotarget, Advance Publications 2014 Mar 15; 5(5): 1382-9
  • Kassim YM, Prasath V. B. S., Pelapur R., Glinskii O. V., Glinsky V. V., Huxley V. H., Maude R. J., Palaniappan K. Random forests for dura mater microvasculature segmentation using epifluorescence images. 38th Annual International Conference EMBS (IEEE EMBS/EMBC), Orlando, USA, Aug 16-20, 2016. Proc. IEEE, pp. 2901--2904.