Rebecca Whiting, PhD

Academic Information

Assistant Research Professor
P. 573-882-8483

Research Interests

  • Therapeutic intervention for retinal degenerative and neurodegenerative disease
  • Objective measures of visual function

Areas of Expertise

  • Retinal degeneration
  • Large animal models
  • Electroretinography
  • Pupillography
  • In vivo retinal imaging

Education & Training

Medical School

Illinois institution of Technology, Chicago, IL; University of Missouri

Graduate

University of Missouri, PhD in Biological Engineering

Undergraduate

Illinois Institute of Technology, Chicago, IL, BS in Biomedical Engineering

Awards & Honors

  • 2016 National Eye institution Travel Grant to present at the Association for Research in Vision and Ophthalmology (ARVO) 2016 Annual Meeting
  • 2011 University of Missouri, Graduate Professional Council Travel Award
  • 2009 Cold Spring Harbor Laboratories course scholarship: ‘Structure, Function and Development of the Visual System’

Publications

Publication focus

  • Tracy CJ, Whiting REH, Pearce JW, Baye G, Vansteenkiste DP, Gillespie LE, Castaner LJ, Bryan JN, Coates JR, Jensen CA, Katz ML. Intravitreal implantation of TPP1-transduced stem cells delays retinal degeneration in canine CLN2 neuronal ceroid lipofuscinosis. Exp. Eye Res. 2016;152:77-87.
  • Whiting REH, Jensen CA, Pearce JW, Gillespie LE, Bristow DE, Katz ML. Intracebroventricular gene therapy that delays neurological disease progression is associated with selective preservation of retinal ganglion cells in a canine model of CLN2 disease. Exp Eye Res 2016; 146:276-282.
  • Katz ML, Tecedor L, Chen Y, Williamson BG, Lysenko E, Wininger FA, Young WM, Johnson GC, Whiting REH, Coates JR, Davidson BL. AAV gene transfer delays onset in a TPP1-deficient canine model of the late infantile form of Batten disease. Science Translational Medicine. 2015; 7(313), 313ra180.
  • Whiting REH, Narfstrom K, Yao G, Pearce JW, Coates JR, Castaner LJ, Vuillemenot B, Kennedy D, O’Neil C, Katz ML.  Enzyme Replacement Therapy Delays Pupillary Light Reflex Deficits in a Canine Model of Late Infantile Neuronal Ceroid Lipofuscinosis.  Exp. Eye Res. 2014; 125: 164-172.

Other Publications

  • Whiting REH, Pearce JW, Castaner L, Jensen CA, Katz RJ, Gilliam, Katz ML.  Multifocal Retinopathy in Dachshunds with CLN2 Neuronal Ceroid Lipofuscinosis.  Exp. Eye Res. 2015; 134: 123-132.
  • Whiting REH, Narfstrom K, Yao G, Pearce JW, Coates JR, Castaner LJ, Katz ML. Pupillary Light Reflex Deficits in a Canine Model of Late Infantile Neuronal Ceroid Lipofuscinosis.  Exp. Eye Res. 2013; 116c: 402-410.
  • Whiting REH, Yao G, Narfstrom K, Pearce JW, Coates JR, Dodam JR, Castaner LJ, Katz ML.  Quantitative Assessment of the Canine Pupillary Light Reflex.  Invest. Ophth. & Visual Science. 2013; 54: 5432–5440.
  • Sanders DN, Kanazono S, Wininger FA, Whiting REH, Flournoy CA, Coates JR, Castaner LJ, O’Brien DP, Katz ML.  A reversal learning task detects cognitive deficits in a Dachshund model of late-infantile neuronal ceroid lipofuscinosis.  Genes, Brain, and Behavior. 2011; 10: 798-804.
  • Thompson S, Whiting REH, Kardon RH, Stone EM, Narfstrom K.  Effects of hereditary retinal degeneration due to a CEP290 mutation on the feline pupillary light reflex.  Vet. Ophthalmology.  2010; 13: 151-157.
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