Richard A. Finkelstein, PhD

Richard A. Finkelstein, PhD

Molecular Microbiology and Immunology

Curators' Professor and Millsap Distinguished Professor Emeritus

573-882-8152

Profile

Enteric pathogenesis, immunology, and vaccine development; epitopes of cholera enterotoxins and related enterotoxins from Escherichia coli, genetically-engineered chimeras, and synthetic peptides; Vibrio cholerae adherence mechanisms and iron-regulated membrane proteins; bacterial zinc-containing metalloproteases; iron and bacterial-host interactions; antimicrobial activity of human and bovine milk; colonial morphology (phase variation) in choleragenic vibrios; choleraphage and choleracins; Burkholderia (Pseudomonas) pseudomallei.

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Academic Information

Curators' Professor and Millsap Distinguished Professor Emeritus
P. 573-882-8152

Research Interests

  • Pathogenesis
  • Immunology

Education & Training

Post-Graduate School

1955, PhD, The University of Texas at Austin

Publications

  1. McCombie, R.L., R.A. Finkelstein, and D.E. Woods. 2006. Multilocus sequence typing of historical Burkholderia pseudomallei isolates collected in southeast Asia from 1964 to 1967 provides insight into the epidemiology of melioidosis. J of Clin. Microbiol. 44:2951-2962.
  2. Benitez, J.A., A. J. Silva, and R.A. Finkelstein.2001. Environmental signals controlling production of hemagglutinin/ protease in Vibrio cholerae. Infect. Immun. 69:6549-6553.
  3. Finkelstein, R.A. 2000. Personal reflections on cholera: The impact of serendipity. Amer. Soc. for Microbiol. (ASM) News. 66:663-667
  4. Finkelstein, R.A., P. Atthasampunna, and M. Chulasamaya.2000. Pseudomonas (Burkholderia) pseudomallei in Thailand, 1964-1967: Geographic distribution of the organism, attempts to identify cases of active infection, and presence of antibody in representative sera. Am. J. Trop. Med. Hyg. 62:232-239.
  5. Peterson, J.W, R.A. Finkelstein, J. Cantu, D.L. Gessell, and A.K. Chopra. 1999. Cholera toxin B-subunit activates arachidonic acid metabolism. Infect. Immun. 67:794-799.
  6. Jouravleva, E.A., G.A. McDonald, J.W. Marsh, R.K. Taylor, M. Boesman-Finkelstein, and R.A. Finkelstein.1998. The Vibrio cholerae mannose-sensitive hemagglutinin is the receptor for a filamentous bacteriophage from V. cholerae O139. Infect Immun . 66:2535-2539.
  7. Finkelstein, R.A., M. Boesman-Finkelstein, D.K. Sengupta, W.J. Page, C.M. Stanley, and T.E. Phillips. 1997. Colonial opacity variations among the choleragenic vibrios. Microbiol. 143:23-34.
  8. Boesman-Finkelstein, M., J.W. Peterson, L.S. Thai, and R.A. Finkelstein.1996. A non-toxic cholera enterotoxin (CT) analog is chimeric with regard to both epitypes of CT-B subunits, CT-B-1 and CT-B-2. Infect. Immun. 64:346-348.