The Department of Orthopaedic Surgery has dedicated significant resources to the pursuit of clinical, translational, and basic science research.
Our state-of-the-art Thompson Lab, housed on the fourth floor of Missouri Orthopaedic Institute (MOI), includes ~12,000 square feet solely dedicated to research for a team of more than 50 researchers representing 13 different specialties.
The lab houses Basic Science and Translational Research, Skeletal Morphology Research, Bioengineering Research, and Clinical Research teams and facilities. MOI houses over 40 clinical faculty specializing in sports medicine (primary care and surgical), joint replacement, pediatrics, hip and knee, foot and ankle, shoulder, hand, spine, trauma, limb preservation, regenerative medicine (Mizzou BioJoint® Center), physical medicine and rehabilitation, and diagnostic imaging.
More than 200 other health care professionals and staff provide care and services including nursing, imaging, prosthetics, pharmacy, physical therapy, occupational therapy, nutrition, and mental health. Our internationally recognized faculty and staff — combined with our state-of-the-art Thompson Lab and variety and volume of patients — create an optimal environment for bedside-to-bench-to-bedside research. See below for a full list of active projects and presentations.
|Research projects||Research presentations|
Featured Clinical Researcher of the Quarter:
Dr. Daniel Hoernschemeyer
Dr. Hoernschemeyer is a pediatric orthopaedic surgeon with a national reputation for treating children with various types of dwarfism. He is the only surgeon in Missouri who provides a less-invasive scoliosis treatment known as Vertebral Body Tethering. He also assisted in the development of a patented plate used in the treatment of pediatric femur fractures, and it is now available in 29 countries.
After his residency at St. Mary’s Medical Center in San Francisco, Dr. Hoernschemeyer completed a pediatric orthopaedics and spine fellowship at Johns Hopkins University. Currently, he serves as co-director of the Pediatric Intensive Care Unit for MU Health Care and is an active member of the Little People of America Medical Advisory Board, American Academy of Orthopaedic Surgeons, Pediatric Orthopaedic Society of North America, and the Scoliosis Research Society.
Dr. Hoernschemeyer is currently leading the following clinical research studies:
- Outcome Measurements of Vertebral Body Tethering for Adolescent Idiopathic Scoliosis
- A Phase III Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study to Evaluate the Efficacy and Safety of BMN 111 in Children with Achondroplasia
- Magnetic Resonance Imaging (MRI) Evaluation of Adolescent Idiopathic Scoliosis (AIS) Patients Who Have Undergone Vertebral Body Tethering (VBT)
- A Phase 3, Open-Label Long-Term Extension Study to Evaluate the Safety and Efficacy of BMN 111 in Children with Achondroplasia
- ACHieve: A Multi-Center, Longitudinal, Observational Study of Children with Achondroplasia