The Department of Orthopaedic Surgery has dedicated significant resources to the pursuit of clinical, translational, and basic science research.
Our state-of-the-art Thompson Lab, housed on the fourth floor of Missouri Orthopaedic Institute (MOI), includes ~12,000 square feet solely dedicated to research for a team of more than 50 researchers representing 13 different specialties.
The lab houses Basic Science and Translational Research, Skeletal Morphology Research, Bioengineering Research, and Clinical Research teams and facilities. MOI houses over 40 clinical faculty specializing in sports medicine (primary care and surgical), joint replacement, pediatrics, hip and knee, foot and ankle, shoulder, hand, spine, trauma, limb preservation, regenerative medicine (Mizzou BioJoint® Center), physical medicine and rehabilitation, and diagnostic imaging.
More than 200 other health care professionals and staff provide care and services including nursing, imaging, prosthetics, pharmacy, physical therapy, occupational therapy, nutrition, and mental health. Our internationally recognized faculty and staff — combined with our state-of-the-art Thompson Lab and variety and volume of patients — create an optimal environment for bedside-to-bench-to-bedside research. See below for a full list of active projects.
Featured Clinical Researcher of the Quarter:
Dr. Matthew Smith
Dr. Smith is an orthopaedic clinician scientist with expertise in diagnosis and treatment of acute and chronic shoulder and elbow problems. His research interests include shoulder arthroscopy, rotator cuff and ligament reconstruction, joint preservation, and prosthetic shoulder replacement. He serves as the shoulder and elbow specialist for the Mizzou BioJoint® Center. He has also led design teams for shoulder arthroplasty systems, elbow arthroplasty systems, and electronic data capture programs with related patents to his credit.
After his residency here at the University of Missouri, Dr. Smith completed a 1-year shoulder and elbow fellowship at the prestigious Rothman Institute at Jefferson Health in Philadelphia. He is one of a handful of surgeons in Missouri elected to the American Shoulder and Elbow Surgeons Society and currently serves as the vice president of the Missouri Shoulder and Elbow Society. Dr. Smith has authored or co-authored more than 20 original scientific publications and works with orthopaedic implant companies in product development, surgeon education, and research for implant survivorship and effectiveness.
Dr. Smith is currently leading the following clinical research studies for the Missouri Orthopaedic Institute:
- Establishing a prospective database of patient clinical visits utilizing survey outcome measurements
- Evaluation of pathologic cell signaling in osteoarthritis of the shoulder
- Tornier shoulder outcomes clinical study (SHOUT)
- Investigator driven, multi-centered, superior capsular reconstruction study
- Pyrocarbon total shoulder replacement system
- Total shoulder arthroplasty multi-center registry
- PCR bacterial profiling in identifying risk factors for total shoulder replacement infections