The Department of Orthopaedic Surgery has dedicated significant resources to the pursuit of clinical, translational, and basic science research.
Our state-of-the-art Thompson Lab, housed on the fourth floor of Missouri Orthopaedic Institute (MOI), includes ~12,000 square feet solely dedicated to research for a team of more than 50 researchers representing 13 different specialties.
The lab houses Basic Science and Translational Research, Skeletal Morphology Research, Bioengineering Research, and Clinical Research teams and facilities. MOI houses over 40 clinical faculty specializing in sports medicine (primary care and surgical), joint replacement, pediatrics, hip and knee, foot and ankle, shoulder, hand, spine, trauma, limb preservation, regenerative medicine (Mizzou BioJoint® Center), physical medicine and rehabilitation, and diagnostic imaging.
More than 200 other health care professionals and staff provide care and services including nursing, imaging, prosthetics, pharmacy, physical therapy, occupational therapy, nutrition, and mental health. Our internationally recognized faculty and staff — combined with our state-of-the-art Thompson Lab and variety and volume of patients — create an optimal environment for bedside-to-bench-to-bedside research. See below for a full list of active projects and presentations.
|Research projects||Research presentations|
Featured Clinical Researcher of the Quarter:
Dr. Sumit Gupta
Dr. Gupta is a pediatric orthopaedic surgeon and treats children who have various orthopaedic conditions, including birth defects, traumatic injuries, and growth deformities. His research interests include developing clear guidelines and management of subungual exostosis — bony tumors on the tips of finger and toes. He has also published work about rotationplasty surgeries for various indications such as malignant bone tumors and congenital limb deformities. In addition, Dr. Gupta served as co-investigator on a study that looked at diagnosis of the discoid meniscus in patients with achondroplasia.
After his residency at McGill University in Montreal, Canada, Dr. Gupta completed fellowships in pediatric orthopaedics at University of Calgary and University of British Columbia. He serves as a member of the practice management committee for the Pediatric Orthopaedic Society of North America (POSNA). In this role, he helps shape the discussion around electronic medical record usage among pediatric orthopaedic surgeons.
Dr. Gupta is currently leading the following clinical research studies at Missouri Orthopaedic Institute:
- Antibiotics Usage in Pediatric Orthopaedic Percutaneous Surgery (APOPS)
- A Phase 4, Open-Label, Single-Dose, Parallel-Group Study to Evaluate the Safety of Cefazolin in Pediatric Subjects
- Post-operative Use of Opioid Analgesics in Pediatric Orthopaedic Patients