The division is engaged in the following scholarly activities.
Research projects
- Smart Monitor for the NICU: Adaptive System for the Detection and Prediction of Apnea, Desaturation and Bradycardia in Premature and Low Birth Weight Infants. Coulter Biomedical Accelerator at the University of Missouri. $104,870 grant. Dates: 7/1/19 to present
- NICU Automatic Oxygen Control with Parameter and Disturbance Estimation. NIH grant $414,149. Dates: 4/10/20 to present
Hou X, Faqeeh A, Amjad R, Pardalos J, Fales R.
Clinical Evaluation of an Automatic Oxygen Control System for Premature Infants Receiving High-Flow Nasal Cannula for Respiratory Support: A Pilot Study
JMed Device. 2022 Sep 1;16(3):031005.
PMID: 35646226
https://pubmed.ncbi.nlm.nih.gov/35646226/ - MedImmune, Inc. – A Phase 3 Randomised, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of MEDI8897, a Monoclonal Antibody With an Extended Half-life Against Respiratory Syncytial Virus, in Healthy Late Preterm and Term Infants (MELODY). Protocol No. D5290C00004. Multicenter trial October, 2019 to present.
- MedImmune, Inc. – A Phase 2/3 Randomized, Double-blind, Palivizumab-controlled Study to Evaluate the Safety of MEDI8896, a Monoclonal Antibody With an Extended Half-life Against Respiratory Syncytial Virus, in High-risk Children (MEDLEY). Protocol No. D5290C00005. Multicenter trial October, 2019 to present.
Completed research projects
- Understanding umbilical venous catheter insertion practices through a prospective multicenter observational study
Patel S, Shannon D, Eldridge W, El-Ters N, Hanford J, Walker T, Scheer A, Jones E, Linwood K, Aragon N, Dunscombe L, Gerbes J, Srinivasan N, Vachharajani A. J Matern Fetal Neonatal Med. 2021 Feb 2:1-6. doi: 10.1080/14767058.2021.1874908. Online ahead of print. PMID: 33530795
https://pubmed.ncbi.nlm.nih.gov/33530795/ - Ultrasound Guided Prospective Screening for Spinal Dysraphism in Offspring of Mothers With Pregestational Diabetes: A Pilot Study
Saivaroon Gajagowni, Danielle Mazuru-Witten, Jessica Hegstrom, Jean Goodman, Akshaya J Vachharajani
PMID: 37792458
DOI: 10.1002/jum.16327
https://pubmed.ncbi.nlm.nih.gov/37792458/
Completed Quality Improvement Projects
- Reducing intravenous catheter insertion in late preterm neonates
Project leaders: Ms. Jennifer Hanford NNP and Dr. Olugbemisola Obi, MD
The project aims to reduce the need for IV catheter insertion and parenteral nutrition in late preterm infants.
https://pubmed.ncbi.nlm.nih.gov/38241696/
Quality Improvement Projects
Improving Care of Infants with Neonatal Abstinence Syndrome
Project Leaders: Dr. Anjali Anders and Amy Lade, RN
Our institution is part of the Missouri Hospital Association-NAS QI Collaborative, which aims to improve care of infants with neonatal abstinence (or opiate withdrawal) syndrome. The goals of this QI include transition to Eat, Sleep Console method of assessment and management of the newborn; increasing non-pharmacological care; keeping mother-infant dyad intact; and validated screening of the mother for substance use disorders to provide early diagnosis and management of substance use disorders prenatally.
