The MU School of Medicine Data & Safety Monitoring Committee (DSMC) serves as a resource for faculty members without access to other multi-site data safety and monitoring boards (DSMBs), especially for investigator-initiated trials. The Health Sciences Institutional Review Board (IRB) also calls on the committee to act as a resource for situations when monitoring may be needed.

Providing Research Oversight & Ensuring Data Integrity

The DSMC helps investigators and MU research compliance oversight mechanisms protect human-research participants and ensure the integrity and scientific validity of research data. To accomplish this mission, the committee:

  • Educates investigators, research teams and faculty on data and safety monitoring
  • Reviews proposed data and safety monitoring plans
  • Establishes data and safety monitoring boards
  • Conducts independent interim reviews of study safety and progress
  • Makes recommendations regarding the continuation of studies, including whether to modify, suspend or terminate a study

For details, download the DSMC Fact Sheet [PDF] and the Data Safety & Monitoring Plan Checklist [Word].


Member Department
Arthur Rawlings, MD Surgery
Syed Naqvi, MD Medicine
David Beversdorf, MD Radiology/Neurology
Lea C. Brandt, OTD, OTR/L Center for Health Ethics
Kelli Canada, PhD, MSW School of Social Work
Greg Alexander, PhD, RN, FAAN, FACMI Sinclair School of Nursing
David Fleming, MD Medicine/Center for Health Ethics
Sonja Grinfeld, PharmD Investigational Drug Service Pharmacist
David Mehr, MD Family and Community Medicine
Mojgan Golzy, PhD Biostatistics Group
Greg Petroski, PhD Biostatistics Group
Shivendra Shukla, PhD Medical Pharmacology/Physiology

Ex Officio Members

Member Department
William Fay, MD School of Medicine Office of Research
Jennifer May, JD Chief Compliance Officer, MU Health Care
Don Reynolds, JD (Executive Secretary) Office for Responsible Research

Investigator Tools

Data and safety monitoring tools available for investigators include:

Committee Tools

For the work of the committee, DSMC members may use the following tools: