Clinical research is focused on new treatments that improve the quality of life of our patients. Many of our patients experience long-term disability because of their injury or disease process. It is our goal to help each patient achieve their maximum potential through our established treatment regimens as well as through our clinical research studies.

Our previous clinical trials have included studies on new treatments for spasticity from spinal cord injury, improving cognitive functions in stroke and head-injury patients, the use of botulinum toxin for post-stroke spasticity and pain management, and new treatment regimens for chronic pain.

Anne Bonnett, RN, CCRC, is the Clinical Research Coordinator for the department. Anne coordinates each clinical trial and assists the physicians with patient study visits. Anne also communicates with the study sponsors and maintains study records for each trial.

We are grateful for the participation of our patients in these clinical trials. You may benefit from our efforts to advance science and medicine through research. If you are interested in volunteering for a clinical trial, see below for details about the clinical trials open for enrollment at this time.

Current Studies in PM&R



Participants are needed to determine if an investigational drug may help relieve muscle tightness in the arm muscles resulting from a stroke or TBI three or more months ago.

To participate you must:

  • Be 18 to 70 years of age
  • Attend up to 13 clinic visits over 39 weeks in Columbia, MO
  • Have tests to measure your muscle tightness
  • Have injections in your arm muscles
  • Meet additional criteria

There is no cost to you to participate. You will receive compensation to help cover your travel expenses. This trial is being conducted by Joseph Burris, MD, at Rusk Rehabilitation Hospital.

For more information:

On the Web:
Study # NCT03821402

Contact: Anne Bonnett, RN