Clinical research is focused on new treatments that improve the quality of life of our patients. Many of our patients experience long-term disability because of their injury or disease process. It is our goal to help each patient achieve their maximum potential through our established treatment regimens as well as through our clinical research studies.
Our previous clinical trials have included studies on new treatments for spasticity from spinal cord injury, improving cognitive functions in stroke and head-injury patients, the use of botulinum toxin for post-stroke spasticity and pain management, and new treatment regimens for chronic pain.
Anne Bonnett, RN, CCRC, is the Clinical Research Coordinator for the department. Anne coordinates each clinical trial and assists the physicians with patient study visits. Anne also communicates with the study sponsors and maintains study records for each trial. Fred Murdock, PhD, our research specialist, is primarily involved with regulatory documentation, compliance and communication with sponsors.
We are grateful for the participation of our patients in these clinical trials. You may benefit from our efforts to advance science and medicine through research. If you are interested in volunteering for a clinical trial, see below for details about the clinical trials open for enrollment at this time.
Current Studies in PM&R
Post Stroke Spasticity Clinical Trial
Do you have problems with muscle tightness in your lower leg because of a stroke?
Participants are needed for a clinical trial to determine if an investigational drug can help relieve this muscle tightness. To participate you must:
• Have had a stroke three or more months ago that caused muscle tightness in your lower leg
• Be 18 to 80 years old
• Attend 11 to 14 visits in Columbia, Mo.
• Have tests to measure your muscle tightness and walking ability
• Meet additional criteria
The trial involves injection of an investigational drug into the muscles of your leg. There is no cost to you to participate. You will receive a small payment to help cover your travel expenses. The trial is being conducted at Rusk Rehabilitation Hospital, an affiliate of Encompass Health and MU Health Care, by Joseph Burris, MD, of the Department of Physical Medicine and Rehabilitation at the University of Missouri.
For more information:
On the Web
Study # NCT01464307
Anne Bonnett, RN