Susan C. Nagel, PhD

Susan C. Nagel, PhD

Obstetrics, Gynecology and Women's Health

Associate Professor
Director, Research Success Center



Dr. Susan Nagel directs a basic and translational science research lab focusing on environmental endocrine disrupting chemicals and how they can program fetal development to alter the risk of adult disease. Her lab was the first to show that chemicals associated with unconventional oil and gas extraction or “Fracking” can disrupt the endocrine system and program development and reproductive endpoints in adulthood.

Dr. Nagel has received the Basil O’Conner Junior Faculty Award from March of Dimes and the Barry Commoner Science in Environmental Service Award for her work on environmental endocrine disrupting chemicals. She has held several leadership positions at the MU School of Medicine, including Director of Resident Research, Chair of Research Council, Founder and Director of the OBGYN Research Success Center, Women in Medicine and Medical Sciences Executive Board, and Council of Faculty and Academic Societies with the Association of American Medical Colleges. She is currently vice chair of the Gordon Research Conference on Environmental Endocrine Disruptors.



Academic Information

Associate Professor
Director, Research Success Center
P. 573-884-3028

Research Interests

  • Estrogen action
  • Endocrine disruption
  • Fetal origins of adult disease
  • Epigenetics
  • Endometriosis

Education & Training


Duke University Medical Center, Durham, North Carolina

Awards & Honors

  • Barry Commoner Science in Environmental Service Award, Missouri Coalition for the Environment 2015
  • March of Dimes Basil O’Connor Award 2007
  • Science Communication Fellow 2007
  • Outstanding Undergraduate Research Mentor Award Nominee 2007
  • Outstanding Undergraduate Research Mentor Award Nominee 2006
  • Gordon Research Conference “Environmental Endocrine Disruptors” Travel Award” 2004

In the News


  • Kassotis, C.D., Tillitt, D.E., Lin, C.-H., McElroy, J.A., Nagel, S.C. 2016. Endocrine-disrupting chemicals and oil and natural gas operations: Potential environmental contamination and recommendations to assess complex environmental mixtures. Environmental Health Perspectives, 124(3): 256-264.
  • Palanza, P., Nagel, S.C., Parmigiani, S., vom Saal, F.S. 2016. Perinatal exposure to endocrine disruptors: Sex, timing and behavioral endpoints. Current Opinion in Behavioral Sciences, 7: 69-75.
  • Kassotis, C.D., Iwanowicz, L.R., Akob, D.M., Cozzarelli, I.M., Mumford, A.C., Orem, W.H., Nagel, S.C. 2016. Endocrine disrupting activities of surface water associated with a West Virginia oil and gas industry wastewater disposal site. Science of the Total Environment, 557-558:901-910
  • Kassotis, C.D., Alvarez, D.A., Taylor, J.A., vom Saal, F.S., Nagel, S.C., Tillitt, D.E. 2015. Characterization of Missouri surface waters near point sources of pollution reveals potential novel atmospheric route of exposure for bisphenol A and wastewater hormonal activity pattern. Science of the Total Environment, 524-525: 384-393.
  • Heindel, J.J., Vom Saal, F.S., Blumberg, B., Bovolin, P., Calamandrei, G., Ceresini, G., Cohn, B.A., Fabbri, E., Gioiosa, L., Kassotis, C., et al. 2015. Parma consensus statement on metabolic disruptors. Environmental Health: A Global Access Science Source, 14(1):54.
  • Bhandari, R.K., Deem, S.L., Holliday, D.K., Jandegian, C.M., Kassotis, C.D., Nagel, S.C., Tillitt, D.E., vom Saal, F.S., Rosenfeld, C.S. 2015. Effects of the environmental estrogenic contaminants bisphenol A and 17α-ethinyl estradiol on sexual development and adult behaviors in aquatic wildlife species. General and Comparative Endocrinology, 214: 195-219.
  • Kassotis, C.D., Klemp, K.C., Vu, D.C., Lin, C.-H., Meng, C.-X., Besch-Williford, C.L., Pinatti, L., Zoeller, R.T., Drobnis, E.Z., et al. 2015. Endocrine-disrupting activity of hydraulic fracturing chemicals and adverse health outcomes after prenatal exposure in male mice. Endocrinology, 156(12): 4458-4473.
  • Hormann, A.M., Vom Saal, F.S., Nagel, S.C., Stahlhut, R.W., Moyer, C.L., Ellersieck, M.R., Welshons, W.V., Toutain, P.-L., Taylor, J.A. 2014. Holding thermal receipt paper and eating food after using hand sanitizer results in high serum bioactive and urine total levels of bisphenol A(BPA). PLoS ONE, 9(10), art. no. e110509.
  • Kassotis, C.D., Tillitt, D.E., Davis, J.W., Hormann, A.M., Nagel, S.C. 2014. Estrogen and androgen receptor activities of hydraulic fracturing chemicals and surface and ground water in a drilling-dense region. Endocrinology, 155(3): 897-907.

Complete list of publications